Gene knockouts in people provide drug safety, effectiveness clues

Some Pakistani people are real knockouts, a new DNA study finds. Knockouts in this sense doesn’t refer to boxing or a stunning appearance, but to natural mutations that inactivate, or “knock out” certain genes. The study suggests that human knockouts could prove valuable evidence for understanding how genes work and for developing drugs. Among 10,503 […]

The Arctic is a final garbage dump for ocean plastic

The Arctic Ocean is a final resting place for plastic debris dumped into the North Atlantic Ocean, new research suggests. A 2013 circumpolar expedition discovered hundreds of tons of plastic debris, from fishing lines to plastic films, ecologist Andrés Cózar of the University of Cádiz in Spain and colleagues report April 19 in Science Advances. […]

We went to the March for Science in D.C. Here’s what happened

The March for Science, Washington, D.C. — On April 22, 2017 — Earth Day — thousands of scientists, science advocates and general enthusiasts rallied on the grounds of the Washington Monument in Washington, D.C., at the first-ever March for Science. The organizers estimate that over 600 sister marches also occurred around the world. The march […]

Ancient DNA bucks tale of how the horse was tamed

DNA from 2,000-year-old stallions is helping rewrite the story of horse domestication. Ancient domesticated horses had much more genetic diversity than their present-day descendants do, researchers report in the April 28 Science. In particular, these ancient horses had many more varieties of Y chromosomes and fewer harmful mutations than horses do now. Previous studies based […]

Mars may not have been born alongside the other rocky planets

Mars may have had a far-out birthplace. Simulating the assembly of the solar system around 4.56 billion years ago, researchers propose that the Red Planet didn’t form in the inner solar system alongside the other terrestrial planets as previously thought. Mars instead may have formed around where the asteroid belt is now and migrated inward […]

Naked singularity might evade cosmic censor

Certain stealthy spacetime curiosities might be less hidden than thought, potentially exposing themselves to observers in some curved universes. These oddities, known as singularities, are points in space where the standard laws of physics break down. Found at the centers of black holes, singularities are generally expected to be hidden from view, shielding the universe […]

Even short-term opioid use can set people up for addiction risks

Even though a sprained ankle rarely needs an opioid, a new study of emergency room patients found that about 7 percent of patients got sent home with a prescription for the potentially addictive painkiller anyway. And the more pills prescribed, the greater the chance the prescription would be refilled, raising concerns about continued use. The […]

Deep heat may have spawned one of the world’s deadliest tsunamis

Chemical transformations in minerals deep beneath the seafloor could explain why Indonesia’s 2004 mega-earthquake was unexpectedly destructive, researchers report in the May 26 Science. The magnitude 9.2 quake and the tsunami that it triggered killed more than 250,000 people, flattened villages, and swept homes out to sea across Southeast Asia. It was one of the […]

For babies exposed to opioids in the womb, parents may be the best medicine

The first thing you’ll notice is the noise. Monitors beep steadily, relentlessly, ready to sound a car-alarm blare if a baby is in trouble. The air has an astringent odor — not clean exactly, but reminiscent of an operating room (there’s one next door). Ceiling lights shine fluorescent white. Half are off, but glare from […]

Swift kick from a supernova could knock a black hole askew

Gravitational waves are providing new hints about how black holes get their kicks. The Advanced Laser Interferometer Gravitational-Wave Observatory’s detection of spacetime ripples from two merging black holes on December 26, 2015, indicated that one black hole was spinning like a tilted top as it orbited with its companion (SN: 7/9/16, p. 8). That off-kilter […]